Haemorheological use of n-alkylated...

Details Haemorheological use of n-alkylated... Haemorheological use of n-alkylated...

C - Chemistry, Metallurgy

07

D

167/229, 260/294

C07D 211/82 (2006.01) A61K 31/455 (2006.01) C07D 211/90 (2006.01)

Patent

CA 2040062

ABSTRACT Improving circulation, with minimal effect on blood pressure, using N-alkylated 1,4-dihydropyridines of the formula (I) Image in which R1 represents hydrogen, nitro, cyano, trifluoromethyl trifluoromethoxy, halogen or methyl, R2 represents hydrogen, halogen, nitro, hydroxyl, trifluoromethyl or methyl, R3 represents hydrogen or cyano, or R2 and R3 together form a fused benzo ring, R4 and R5 are identical or different and represent straight-chain or branched alkyl having up to 8 carbon atoms, which is optionally substituted by alkoxy having up to 4 carbon atoms, and R6 represents straight-chain or branched alkyl having up to 10 carbon atoms or represents cycloalkyl having 3 to 7 carbon atoms, Many of the compounds are new.

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