A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/445 (2006.01) A61K 8/02 (2006.01) A61K 8/49 (2006.01) A61K 9/06 (2006.01) A61K 9/08 (2006.01) A61K 9/70 (2006.01) A61P 17/14 (2006.01) A61Q 7/00 (2006.01)
Patent
CA 2475385
It is intended to provide hair growth stimulants which contain compounds having a choline esterase inhibitory effect and stimulating hair growth. As the compound having a choline esterase inhibitory effect, compounds having an acetylcholine esterase inhibitory effect are preferable and donepezil hydrochloride has a particularly efficacious effect of stimulating hair growth. It is also intended to provide percutaneous preparations which contain compounds having a choline esterase inhibitory effect such as donepezil and thus exert an effect of simulating hair growth. These percutaneous preparations are preferably in the form of solutions, creams, ointments, plasters or tapes. Moreover, a method of simulating hair growth involving the step of applying donepezil to the scalp is provided.
La présente invention a trait à des stimulants de la pousse de cheveux qui contiennent des composés présentant un effet d'inhibition de la cholinestérase et de stimulation de la pousse de cheveux. En ce qui concerne le composé à effet d'inhibition de cholinestérase, les composés présentant un effet d'inhibition d'acétylcholinestérase sont préférés et le chlorhydrate de donepezil a un effet particulièrement efficace de stimulation de la pousse de cheveux. L'invention a trait également à des préparations percutanées qui contiennent des composés présentant un effet d'inhibition de la cholinestérase tel que le donepezil et donc exerce un effet de croissance de la pousse de cheveux. Ces préparations percutanées sont, de préférence, sous forme de solutions, crèmes, onguents, emplâtres ou bandes. En outre, l'invention a trait à un procédé de stimulation de la pousse des cheveux comportant une étape d'application de donepezil sur le cuir chevelu.
Kato Akira
Kato Takashi
Mizuno Mitsuru
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Eisai Co. Ltd.
Eisai R&d Management Co. Ltd.
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