Halo- or hydroxy-substituted nocathiacin antibiotics

Details Halo- or hydroxy-substituted nocathiacin antibiotics Halo- or hydroxy-substituted nocathiacin antibiotics

C - Chemistry, Metallurgy

12

P

C12P 21/04 (2006.01) C12P 17/14 (2006.01) C12P 17/18 (2006.01) C12P 19/60 (2006.01)

Patent

CA 2372961

Fermentattion of Nocardia sp- ATCC-202099 in the presence of a halogen- or hydroxy-substituted tryptophan precursor yields a novel corresponding halogen- or hydroxy-substituted nocathiacin compound which has broad spectrum antibiotic activity against Gram-positive bacteria and has in vivo efficacy in animals.

La fermentation de Nocardia sp- ATCC-202099 en présence d'un précurseur de tryptophane substitué par halogène ou hydroxy donne un nouveau composé de nocathiacine substituée par halogène ou hydroxy correspondant, qui présente une activité antibiotique à large spectre contre des bactéries gram-positif et une efficacité in vivo chez l'animal.

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