Haloalkyl containing compounds as cysteine protease inhibitors

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 317/28 (2006.01) A61K 31/277 (2006.01) A61P 11/06 (2006.01) A61P 19/02 (2006.01) C07C 255/48 (2006.01)

Patent

CA 2743749

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

La présente invention concerne des composés qui sont des inhibiteurs de cystéine protéases, en particulier, des cathepsines B, K, L, F, et S et sont donc utiles dans le traitement de maladies véhiculées par ces protéases. La présente invention concerne des compositions pharmaceutiques comprenant ces composés et des procédés pour préparer celles-ci.

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