C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 217/54 (2006.01) A61K 31/00 (2006.01) C07C 235/44 (2006.01) C07C 255/55 (2006.01) C07C 263/14 (2006.01) C07C 317/32 (2006.01) C07C 321/28 (2006.01) C07D 209/88 (2006.01) C07D 233/60 (2006.01) C07D 277/24 (2006.01) C07D 277/64 (2006.01) C07D 277/66 (2006.01) C07D 295/182 (2006.01) C07D 295/26 (2006.01) C07D 311/36 (2006.01) C07D 317/46 (2006.01)
Patent
CA 2706465
The present invention is related to the preparation and pharmaceutical use of novel haloallylamine derivatives as SSAO/VAP-1 inhibitors having the structure of Formula I, as defined in the specification:(I). The invention also relates to methods of using invention compounds, or pharmaceutically acceptable salt or derivatives thereof, for the treatment of a variety of indications, e.g., inflammatory diseases.
La présente invention porte sur la préparation et l'utilisation pharmaceutique de nouveaux dérivés d'haloallylamines comme inhibiteurs de SSAO/VAP-1 ayant la structure de la formule (I), telle que définie dans la description : (I). L'invention porte également sur des procédés d'utilisation des composés de l'invention, ou de sels pharmaceutiquement acceptables ou dérivés de ceux-ci, pour le traitement d'une diversité d'indications, par exemple de maladies inflammatoires.
Deodhar Mandar
Foot Jonathan Stuart
Mcdonald Ian Alexander
Turner Craig Ivan
Gowling Lafleur Henderson Llp
Pharmaxis Ltd.
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