C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/505 (2006.01) A61K 31/517 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 403/14 (2006.01)
Patent
CA 2737219
The present invention provides novel analogs and derivatives of halofuginone. The invention also provides pharmaceutical and cosmetic compositions thereof and methods for using halofuginone analogs in treating chronic inflammatory diseases, autoimmune diseases, dry eye syndrome, fibrosis, scar formation, angio--genesis, viral infections, ischemic damage, transplant and implant rejection, neurodegenerative diseases, and cosmetic applications.
La présente invention porte sur de nouveaux analogues et dérivés de l'halofuginone. L'invention porte également sur des compositions pharmaceutiques et cosmétiques de ceux-ci et sur des procédés d'utilisation d'analogues d'halofuginone dans le traitement de maladies inflammatoires chroniques, de maladies auto-immunes, de la kérato-conjonctivite sèche, d'une fibrose, de la formation de cicatrice, de l'angiogenèse, d'infections virales, d'un dommage ischémique, d'un rejet de greffe et d'implant, de maladies neurodégénératives et dans des applications cosmétiques.
Keller Tracy
Lee Jinbo
Mazitschek Ralph
Whitman Malcolm
Gowling Lafleur Henderson Llp
President And Fellows Of Harvard College
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