Halogen substituted benzodiazepine derivatives

Details Halogen substituted benzodiazepine derivatives Halogen substituted benzodiazepine derivatives

C - Chemistry, Metallurgy

07

D

C07D 487/14 (2006.01) A61K 31/55 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2584757

The invention relates to halogen substituted imidazo [1,5-a] [1,2,4] triazolo [1,5~d] [1,4]benzodiazepine derivatives of formula (I), and to their pharmaceutically acceptable acid addition salts. The compounds may be used for the treatment of cognitive enhancer, cognitive disorders, anxiety, Alzheimer's disease and schizophrenia.

L'invention concerne des dérivés d'imidazo [1,5-a] [1,2,4] triazolo [1,5-d] [1,4]benzodiazépine à substitution halogène, représentés par la formule (I), et leurs sels d'addition d'acide pharmaceutiquement acceptables. Ces composés sont utiles comme agents d'amélioration cognitive et dans le traitement de troubles cognitifs, de l'anxiété, de la maladie d'Alzheimer et de la schizophrénie.

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