Halogen-substituted quinoline derivatives and ectoparasite...

Details Halogen-substituted quinoline derivatives and ectoparasite... Halogen-substituted quinoline derivatives and ectoparasite...

C - Chemistry, Metallurgy

07

D

C07D 215/233 (2006.01) A61K 31/47 (2006.01) A61P 33/14 (2006.01) C07D 215/22 (2006.01)

Patent

CA 2443484

An objective of the present invention is to provide an ectoparasite control agent for homothermic animals, which has high control effect and is safe. The compounds according to the present invention are compounds represented by formula (I) and salts thereof: (see formula I) wherein R1 represents optionally substituted alkyl; optionally substituted alkenyl; optionally substituted alkynyl; OR5 wherein R5 represents optionally substituted alkyl, optionally substituted alkenyl, or optionally substituted alkynyl; or SR5 wherein R5 is as defined above, R2 represents optionally substituted alkyl, any one of R3 and R4 represents hydrogen and the other represents fluorine, chlorine, bromine, or CF3, and X represents fluorine or chlorine.

La présente invention concerne des agents d'élimination des ectoparasites destinés aux animaux à sang chaud qui présentent un puissant effet de régulation et une grande sécurité, tels que des composés représentés par la formule (I) ou les sels de ces derniers. Dans la formule (I), R?1¿ représente alkyle éventuellement substitué, alcényle éventuellement substitué, alcynyle éventuellement substitué, OR?5¿ (dans lequel R?5¿ représente alkyle éventuellement substitué, alcényle éventuellement substitué, ou alcynyle éventuellement substitué) ou SR?5¿ (dans lequel R?5¿ est tel que décrit ci-avant) ; R?2¿ représente alkyle éventuellement substitué ; R?3¿ et R?4¿ tels que lorsque l'un représente hydrogène l'autre représente fluoro, chloro, bromo ou CF¿3 ?; et X représente fluoro ou chloro.

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