C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 319/20 (2006.01) C07C 319/14 (2006.01) C07C 323/03 (2006.01) C07C 323/12 (2006.01) C07C 335/08 (2006.01) C07C 335/32 (2006.01)
Patent
CA 2462237
A process for preparing an intermediate compound of formula (II) where n is an integer of from 3 to 14; R1 is haloC1-10alkyl, C1-10alkyl, C2-10alkenyl, C2- 10cycloalkyl, carboxyC1-10alkyl, C1-10alkoxycarbonylC1-10alkyl, aryl (such as phenyl), aryl(C1-10)alkyl (such as phenyl(C1-10)alkyl) or di(C1-6alkyl)amino; and R2 is a halo group; the process comprising halogenation of a compound of formula (III) where n and R1 are as defined above. The compounds of formulae (IIIA, IIIB, IV) and derivatives are also claimed.
L'invention concerne un procédé permettant de préparer un composé intermédiaire représenté par la formule (II), où : n est un entier compris entre 3 et 14 ; R?1¿ représente haloC¿1-10?alkyle, C¿1-10?alkyle, C¿2-10?alcényle, C¿2-10?cycloalkyle, carboxyC¿1-10?alkyle, C¿1-10?alcoxycarbonylC¿1-10?alkyle, aryle (tel que phényle), aryl(C¿1-10?)alkyle (tel que phényl(C¿1-10?)alkyle) ou di(C¿1-6?alkyl)amino; et R?2¿ représente un groupe halo. Le procédé comprend l'halogénation d'un composé représenté par la formule (III), où n et R?1¿ sont tels que définis ci-dessus. L'invention a également trait aux composés représentés par les formules (IIIA), (IIIB), (IV) et à leurs dérivés.
Kane Anne Margaret Lamont
Warren Kenneth Edwin Herbert
Astrazeneca Ab
Fetherstonhaugh & Co.
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