Halogenophenyl glyceride esters

Details Halogenophenyl glyceride esters Halogenophenyl glyceride esters

C - Chemistry, Metallurgy

07

C

260/483.1, 260/4

C07C 69/353 (2006.01) C07C 59/68 (2006.01) C07C 69/58 (2006.01)

Patent

CA 1221983

ABSTRACT OF THE DISCLOSURE HALOGENOPHENYL GLYCERIDE ESTERS The invention concerns novel glyceride esters of anti- bacterial halogenated phenols having the formula I Image in which Ra and Rb are independently (3-20C)alkyl or (3-20C)al- kenyl; Rc and Rd are independently chloro or bromo; Re is hydro- gen, chloro or bromo; and A is (1-6C)alkylene optionally bearing one or two (1-4C)alkyl substituents. The esters are of use in the prophylaxis and/or therapy of acne vulgaris. Pharmaceutical com- positions for topical administration and processes for the manu- facture of the esters are also provided.

430604

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