Hamster ef-1.alpha. transcriptional regulatory dna

Details Hamster ef-1.alpha. transcriptional regulatory dna Hamster ef-1.alpha. transcriptional regulatory dna

C - Chemistry, Metallurgy

12

N

C12N 15/85 (2006.01) C07K 14/47 (2006.01) C12N 15/11 (2006.01) C12N 15/67 (2006.01)

Patent

CA 2259145

The present invention relates to regulatory DNA sequences derived from the hamster EF-1.alpha. gene. The invention further encompasses expression constructs comprising regulatory DNA of the invention, host cells transformed or transfected with the regulatory DNA and methods of increasing gene transcription utilizing the regulatory DNA. Expression constructs comprising regulatory DNA of the invention operably linked to specific gene sequences are also comprehended.

L'invention porte sur des séquences d'ADN régulateur dérivant du gène EF-1 alpha du hamster. L'invention porte également sur des produits d'assemblage d'expression comprenant le susdit ADN régulateur, sur des cellules hôtes transformées ou transfectées par le susdit ADN régulateur, et sur des procédés augmentant la transcription des gènes recourant au susdit ADN régulateur. Les produits d'assemblage d'expression comprenant le susdit ADN régulateur fonctionnellement lié à des séquences spécifiques de gènes font également partie de l'invention.

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