A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/48 (2006.01) A23L 1/302 (2006.01)
Patent
CA 2063791
Hard gelatin capsules contain: (a) a fat-soluble nutrient, such as a fat- soluble vitamin (A, D, E or K) or an unsaturated fatty acid glyceride; (b) a nonionic surfactant, such as a polyoxyethylated (optionally hydrogenated) pastor oil; and/or a polyethylene glycol; (c) a gelatin softening agent such as glycerol, propylene glycol or, preferably, glyceryl mono-oleate; and optionally (d) water: The problems of embrittlement conventionally encountered with hard gelatin capsules containing fat-soluble nutrients are reduced or avoided.
Capsules dures de gélatine contenant: (a) un nutriment soluble dans la matière grasse, tel qu'une vitamine (A, D, E ou K) soluble dans de la matière grasse ou un glycéride d'acide gras insaturé; (b) un tensio-actif non ionique tel qu'une huile de ricin polyoxyéthylée (facultativement hydrogénée), et/ou un polyéthylène glycol; (c) un agent adoucissant la gélatine tel que le glycérol, le propylène glycol ou, de préférence, du mono-oléate de glycéryle; et facultativement (d) de l'eau. Ainsi, on réduit ou on évite les problèmes de fragilité rencontrés habituellement avec les capsules dures de gélatine contenant des nutriments solubles dans la matière grasse.
Gowling Lafleur Henderson Llp
Pii Drug Delivery Llc
LandOfFree
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