Hard gelatine capsule containing fat-soluble nutrients.

A - Human Necessities – 61 – K

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A61K 9/48 (2006.01) A23L 1/302 (2006.01)

Patent

CA 2063791

Hard gelatin capsules contain: (a) a fat-soluble nutrient, such as a fat- soluble vitamin (A, D, E or K) or an unsaturated fatty acid glyceride; (b) a nonionic surfactant, such as a polyoxyethylated (optionally hydrogenated) pastor oil; and/or a polyethylene glycol; (c) a gelatin softening agent such as glycerol, propylene glycol or, preferably, glyceryl mono-oleate; and optionally (d) water: The problems of embrittlement conventionally encountered with hard gelatin capsules containing fat-soluble nutrients are reduced or avoided.

Capsules dures de gélatine contenant: (a) un nutriment soluble dans la matière grasse, tel qu'une vitamine (A, D, E ou K) soluble dans de la matière grasse ou un glycéride d'acide gras insaturé; (b) un tensio-actif non ionique tel qu'une huile de ricin polyoxyéthylée (facultativement hydrogénée), et/ou un polyéthylène glycol; (c) un agent adoucissant la gélatine tel que le glycérol, le propylène glycol ou, de préférence, du mono-oléate de glycéryle; et facultativement (d) de l'eau. Ainsi, on réduit ou on évite les problèmes de fragilité rencontrés habituellement avec les capsules dures de gélatine contenant des nutriments solubles dans la matière grasse.

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