Hardening agent for phase separation microencapsulation

B - Operations – Transporting – 01 – J

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167/166, 117/46.

B01J 13/06 (2006.01) A61K 9/16 (2006.01) A61K 9/52 (2006.01) B01J 13/12 (2006.01) B01J 13/20 (2006.01)

Patent

CA 1330533

IMPROVED PHASE SEPARATION MICROENCAPSULATION PROCESS AND PHARMACEUTICAL COMPOSITIONS PRODUCED THEREBY ABSTRACT There is disclosed a process for preparing compo- sitions comprising microcapsules by phase separation microencapsulation wherein the hardening agent employed is a volatile silicone fluid and with the compositions prepared thereby. The use of the volatile silicone fluid as a hardening agent permits the production of micro- capsules substantially free of any alkane hardening agent, eliminating potential combustability problems of the prior art processes and toxicity problems of the prior art compositions.

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