Hbv surface antigen particles, prepared by recombinant dna...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/00 (2006.01) A61K 39/29 (2006.01) A61K 39/295 (2006.01) C07K 14/02 (2006.01) C07K 14/10 (2006.01) C07K 14/105 (2006.01) C07K 14/155 (2006.01) C07K 14/445 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1341074

HBV surface antigen particles, prepared by recombinant DNA technology are described, said particles being composed of epitopes from the group of surface peptides and/or core peptide of non-A, non-B hepatitis virus, hepatitis virus A and/or hepatitis virus B. Respective particles are especially characterized by a composition of different epitopes selected from pre-S and S peptides. There are also described DNA-sequences, plasmids and cell lines coding for respective HBV surface antigen particles as well as a new vaccine containing the same.

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