Hcv assay

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/70 (2006.01) G01N 33/549 (2006.01) G01N 33/576 (2006.01)

Patent

CA 2498228

An HCV antigen/antibody/antigen assay is provided. The assay employs an isolated first antigen from a region of the HCV polyprotein, and an HCV multiple epitope fusion antigen that includes an epitope from the same region of the polyprotein as the first antigen. Both the first antigen and the multiple epitope fusion antigen bind antibodies present in an HCV-infected sample.

L'invention porte sur un dosage biologique antigène/anticorps/antigène relatif au virus de l'hépatite C. Le dosage biologique utilise un premier antigène isolé d'une région de la polyprotéine du virus de l'hépatite C et un antigène de fusion à plusieurs épitopes du virus de l'hépatite C qui comprend un épitope issu de la même région de la polyprotéine que celui du premier antigène. Le premier antigène et l'antigène de fusion à plusieurs épitopes se lient aux anticorps présents dans l'échantillon infecté par le virus de l'hépatite C.

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