Hcv core protein sequences

Details Hcv core protein sequences Hcv core protein sequences

C - Chemistry, Metallurgy

07

K

C07K 14/18 (2006.01) G01N 33/576 (2006.01) G01N 33/577 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2408174

The present invention describes peptides and recombinant proteins containing Hepatitis C virus core protein sequence in which one or more of the amino acids have been modified or deleted to remove the ability of these proteins to bind to specific anti-HCV murine monoclonal antibodies. The deletions and modifications are designed as to maintain the ability of this protein to be used in immunoassays used for the detection of anti- HCV antibodies in individuals infected with HCV.

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