Hcv inhibitors and methods of using them

Details Hcv inhibitors and methods of using them Hcv inhibitors and methods of using them

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4709 (2006.01) A61K 31/4745 (2006.01) A61P 31/12 (2006.01) C07D 215/54 (2006.01) C07D 471/14 (2006.01) C07D 491/14 (2006.01)

Patent

CA 2540021

The present invention comprises tetrazoloquinoline-compounds that are inhibitors of HCV. Compositions comprising the compounds in combination with a pharmaceutically acceptable carrier are also disclosed, as are methods of using the compounds and compositions to inhibit HCV infection of a cell, particular in the form of treating HCV infection in a mammal.

La présente invention concerne des composés tétrazoloquinoline qui constituent des inhibiteurs du virus de l'hépatite C (VHC). Cette invention concerne également des compositions renfermant ces composés combinés à un excipient pharmaceutiquement acceptable ainsi que des méthodes d'utilisation de ces composés et compositions pour inhiber une infection par le VHC d'une cellule et en particulier des méthodes de traitement d'une infection par le VHC chez un mammifère.

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