Hcv polymerase suitable for crystal structure analysis and...

Details Hcv polymerase suitable for crystal structure analysis and... Hcv polymerase suitable for crystal structure analysis and...

C - Chemistry, Metallurgy

12

N

C12N 9/12 (2006.01) C07K 14/18 (2006.01) C12N 15/11 (2006.01) C12Q 1/00 (2006.01) C12Q 1/48 (2006.01) C12Q 1/70 (2006.01) G01N 33/573 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2310896

An HCV polymerase suitable for crystal structural analysis and a method for using the enzyme are provided. The HCV polymerase suitable for crystal structural analysis and/or comprising high HCV polymerase activity can be used for the three-dimensional structural analysis, and for rational identification of HCV polymerase inhibitors by computers. The enzyme can also be used for efficiently evaluating the HCV polymerase-inhibitory activity. The evaluation can be more efficiently performed by combining identification by computers.

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