Heat-generating ceramics body for hyperthermia and method of...

C - Chemistry – Metallurgy – 04 – B

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C04B 35/26 (2006.01) A61K 9/20 (2006.01) A61K 9/50 (2006.01) A61K 41/00 (2006.01) A61L 27/42 (2006.01) A61L 27/54 (2006.01) C03C 4/00 (2006.01) C03C 10/00 (2006.01) C03C 14/00 (2006.01) C04B 35/057 (2006.01) C04B 35/14 (2006.01)

Patent

CA 1340870

An excellent heat-generating ceramics body for hyperthermia of cancers is provided, comprising ferromagnetic ferrite particles, and a bioactive inorganic material layer surrounding the ferrite particles. The inorganic material layer has a composition to form apatite in a living body when embedded therein which has a high affinity to surrounding tissues of a living body and a property of not being perceived as a foreign material by the surrounding tissues by forming an apatite structure thereon, and the ferrite particles exhibits a highly efficient magnetic induction heat generation in an alternative magnetic field, without liberating noxious ions therefrom. The heat-generating ceramics body is particularly useful for deep cancers like bone tumors, can be applied in various shapes of powder, shaped bulk form or fiber depending on administration means, and can be used continuously or for a long period without an adverse influence. Methods of producing the same are also provided.

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