Heat shock genes and proteins from neisseria meningitidis,...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) C07K 14/22 (2006.01) C07K 14/38 (2006.01) C07K 14/40 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2352608

Methods and compositions comprising isolated nucleic acid molecules specific to Neisseria meningitidis, Candida glabrata and Aspergillus fumigatus heat shock proteins (Hsps), as well as vector constructs and isolated polypeptides specific to the same are provided. Such compositions and methods are useful for the diagnosis of infections by these organisms and for generating an immune response to the organisms.

L'invention concerne des procédés et des compositions comprenant des molécules d'acides nucléiques isolés spécifiques aux protéines du stress (hsps) de Neisseria meningitidis, de Candida glabrata et de Aspergillus fumigatus ainsi que des structures de vecteurs et des polypeptides isolés spécifiques à celles-ci. Ces compositions et procédés sont utiles dans le diagnostic des infections provoquées par ces organismes et dans la génération de réponses immunitaires à ces organismes.

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