Heat stable mutants of starch biosynthesis enzymes

C - Chemistry – Metallurgy – 12 – N

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C12N 15/54 (2006.01) A01H 3/00 (2006.01) A01H 5/00 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12N 15/82 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2272128

The subject invention pertains to novel mutant polynucleotide molecules that encode enzymes that have increased heat stability. These polynucleotides, when expressed in plants, result in increased yield in plants grown under conditions of heat stress. The polynucleotide molecules of the subject invention encode maize endosperm ADP glucose pyrophosphorylase (AGP) and soluble starch synthase (SSS) enzyme activities. Plants and plant tissue bred to contain, or transformed with, the mutant polynucleotides, and expressing the polypeptides encoded by the polynucleotides, are also contemplated by the present invention. The subject invention also concerns methods for isolating polynucleotides and polypeptides contemplated within the scope of the invention. Methods for increasing yield in plants grown under conditions of best stress are also provided.

L'invention concerne des nouvelles molécules polynucléotidiques mutantes qui codent des enzymes présentant une stabilité à la chaleur accrue. Ces polynucléotides, lorsqu'ils sont exprimés dans des plantes, permettent d'assurer un rendement élevé dans les plantes ayant poussé dans des conditions de thermostress. Les molécules polynucléotidiques de l'invention codent pour les activités de l'ADP glucose pyrophosphorylase et de la synthase d'amidon solide de l'endosperme du maïs. Les plantes et le tissu végétal sélectionnés de sorte qu'ils contiennent les polynucléotides mutants, ou transformés à l'aide de ces derniers, et exprimant les polypeptides codés par les polynucléotides, sont également décrits. L'invention porte encore sur des méthodes d'isolement de polynucléotides et de polypeptides de l'invention, ainsi que sur des méthodes pour augmenter le rendement dans des plantes cultivées dans les meilleures conditions de stress.

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