C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) C07K 16/00 (2006.01) C12N 15/67 (2006.01) C12N 15/85 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2689125
The current invention comprises a nucleic acid encoding the amino acid sequence of the C-terminal part of the CH3-domain of an immunoglobulin of the class IgA or IgG, or the C-terminal part of the CH4-domain of an immunoglobulin of the class IgE or IgM, wherein the glycine-lysine-dipeptide comprised in the amino acid sequence of the C-terminal part of the CH3- or CH4-domain is encoded by the nucleic acid ggaaaa, or the nucleic acid ggcaaa, or the nucleic acid gggaaa, or the nucleic acid gggaag, or the nucleic acid ggcaag, or the nucleic acid ggaaag.
La présente invention comprend un acide nucléique codant pour la séquence d'acides aminés de la partie C-terminale du domaine CH3 d'une immunoglobuline de la classe IgA ou IgG, ou la partie C-terminale du domaine CH4 d'une immunoglobuline de la classe IgE ou IgM, le dipeptide glycine-lysine compris dans la séquence d'acides aminés de la partie C-terminale du domaine CH3 ou CH4 étant codé par l'acide nucléique ggaaaa, ou l'acide nucléique ggcaaa, ou l'acide nucléique gggaaa, ou l'acide nucléique gggaag, ou l'acide nucléique ggcaag, ou l'acide nucléique ggaaag.
Goepfert Ulrich
Hansen Silke
Knoetgen Hendrik
Kopetzki Erhard
Ploettner Oliver
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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