Hedgehog and patched antagonists for inhibiting cell and...

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) A61K 38/17 (2006.01) C07K 16/18 (2006.01) C07K 16/46 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2343335

A method for inhibiting growth or differentiation of an epithelial cell comprising contacted at least an epithelial cell with an effective amount of agent selected from the group consisting of a hedgehog antagonist and patched antagonist.

L'invention concerne une méthode, permettant d'inhiber la croissance ou la différenciation d'une cellule épithéliale, consistant à mettre en contact au moins une cellule épithéliale avec une quantité efficace d'un agent sélectionné dans le groupe constitué par un antagoniste <=hérisson>= et un antagoniste en pièces.

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