Helicobacter proteins and vaccines

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/106 (2006.01) A61K 31/4164 (2006.01) A61K 31/43 (2006.01) A61K 31/7048 (2006.01) A61K 33/00 (2006.01) A61K 39/39 (2006.01) A61P 1/04 (2006.01) A61P 31/04 (2006.01) A61P 37/04 (2006.01) C07K 14/195 (2006.01) C07K 14/205 (2006.01) C07K 16/12 (2006.01)

Patent

CA 2194236

A vaccine includes at least one Helicobacter, especially Helicobacter pylori protein to which immunoreactivity is detected in H. pylori negative individuals. The Helicobacter proteins are preferably less than 30 kDa and the vaccine especially includes 24 to 25 kDa and/or 18 to 19 kDa proteins. The vaccine may include interleukin (12) as an adjuvant.

La présente invention concerne au moins une protéine d'Helicobacter, en l'occurrence une protéine d'Helicobacter pylori contre laquelle une immunoréactivité a été détectée chez des individus H.Pylori-négatifs. Les protéines d'Helicobacter sont de préférence inférieures à 30 kDa, et le vaccin comprend des protéines de 24 à 25 kDa et/ou de 18 à 19 kDa. Le vaccin peut comporter de l'interleukine 12 comme adjuvant.

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