Helicobacter pylori antigenic protein preparation and...

Details Helicobacter pylori antigenic protein preparation and... Helicobacter pylori antigenic protein preparation and...

C - Chemistry, Metallurgy

07

K

C07K 14/205 (2006.01) C07K 16/12 (2006.01) G01N 33/543 (2006.01) G01N 33/555 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2194237

A Helicobacter pylori protein preparation depleted of H. pylori antigens to which immunoreactivity is detected in H. pylori negative individuals and immunoassays using the protein preparation are described. The protein preparation is depleted of H. pylori antigens less than 30 kDa, especially 24 to 25 kDa and/or 18 to 19 kDa antigens.

La présente invention concerne une préparation à base de protéine d'Helicobacter pylori obtenue par déplétion d'antigènes de H. pylori contre lesquels il a été décelé une immunoréactivité chez des individus H. pylori-négatifs. L'invention concerne également des dosages immunologiques utilisant cette préparation protéinique. La préparation est obtenue par déplétion d'antigènes de H. pylori inférieurs à 30 kDa, en l'occurrence d'antigènes de 24 à 25 kDa et/ou de 18 à 19 kDa.

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