Hematopoietic inhibiting factor containing compositions

Details Hematopoietic inhibiting factor containing compositions Hematopoietic inhibiting factor containing compositions

C - Chemistry, Metallurgy

07

K

C07K 14/475 (2006.01) A61K 35/16 (2006.01) A61K 38/18 (2006.01) A61M 1/16 (2006.01) A61M 1/34 (2006.01) C07K 1/34 (2006.01) C07K 14/47 (2006.01) C07K 14/52 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2129436

- 17 - Abstract The present invention relates to hematopoietic inhibiting factor-containing compositions which inhibit colony formation of CFU-E, comprising a substance obtained in the fraction eluting at exclusion limit by gel filtration using a gel having maximum molecular weight fractionation of not less than 200,000 and not more than 1,500,000, of a dialysate of blood which is obtained with a dialysis membrane having albumin sieving coefficient of not less than 0.01, followed by concentration with a membrane having molecular weight fractionation of not more than 5,000, and hematopoietic inhibiting factor-containing compositions which inhibit colony formation of CFU-E can be obtained. It further relates to a process of treating blood in which AI component is so removed as to satisfy AI/AA ? 1/50, wherein AI is the height of the absorbancy value of the hematopoietic inhibiting factor-containing compositions according to claims 1 - 5 and AA is the height of the maximum absorbancy value in a gel filtration pattern of solutes of the dialysate expressed in terms of the absorbancy at 280 nm, and to a dialysis membrane which satisfies AI/AA ? 1/50, wherein AI is the height of the absorbancy value of the hematopoietic inhibiting factor-containing compositions according to claims 1 - 5 and AA is the height of the maximum absorbancy value in a gel filtration pattern of solutes of the dialysate expressed in terms of the absorbancy at 280 nm. It further relates to drug compositions and a therapeutic agent for erythrocytosis, containing such hematopoietic inhibiting factor as the active ingredient.

Affiliated with

Also associated with

Rating

Hematopoietic inhibiting factor containing compositions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hematopoietic inhibiting factor containing compositions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hematopoietic inhibiting factor containing compositions will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1907836