C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/88 (2006.01) A61K 9/127 (2006.01) A61K 9/16 (2006.01) A61K 31/70 (2006.01) A61K 47/48 (2006.01)
Patent
CA 2187312
Methods and compositions are described for the directed delivery of ribozymes or other compounds to specific cells which express the heme receptor on their surface using heme-bearing microparticles. Such microparticles are useful in the directed delivery and accumulation of drugs designed to treat hepatic diseases such as viral hepatitis or hepatoma.
L'invention porte sur des procédés et compositions utilisés pour la libération dirigée de ribozymes ou autres composés sur des cellules spécifiques exprimant le récepteur d'hème sur leur surface à l'aide de microparticules porteuses d'hème. Ces microparticules sont utiles dans la libération dirigée et l'accumulation de médicaments conçus pour traiter les maladies hépatiques, telles que l'hépatite virale ou l'hépatome.
George Shaji T.
Takle Garry B.
Bereskin & Parr
Innovir Laboratories Inc.
Ribozyme Pharmaceuticals Inc.
Yale University
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