Heme oxygenase inhibitors for the treatment of a microbial...

A - Human Necessities – 61 – K

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A61K 31/4406 (2006.01) A61K 31/135 (2006.01) A61K 31/155 (2006.01) A61K 31/404 (2006.01) A61K 31/437 (2006.01) A61K 31/444 (2006.01) A61P 31/00 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2658877

Inhibitors of microbial heme oxygenase and their use for treatment of microbial infections and bioremediation. The inhibitors of microbial heme oxygenase are useful against a new class of antimicrobial agents to target infections that are persistently difficult to combat with the current spectrum of antimicrobial agents. Screening methods for selecting inhibitors of microbial heme oxygenase.

L'invention concerne des inhibiteurs de l'hème oxygénase microbienne et leur utilisation pour le traitement d'infections microbiennes et pour la bioremédiation. Les inhibiteurs de l'hème oxygénase microbienne sont utiles contre une nouvelle classe d'agents antimicrobiens pour cibler des infections qui difficiles à combattre de façon persistante avec le spectre courant des agents antimicrobiens. L'invention concerne également des procédés de criblage pour sélectionner des inhibiteurs de l'hème oxygénase microbienne.

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