Hemiasterlin derivatives and uses thereof

Details Hemiasterlin derivatives and uses thereof Hemiasterlin derivatives and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 5/00 (2006.01) A61K 31/395 (2006.01) A61K 38/04 (2006.01) A61K 38/05 (2006.01) C07K 1/06 (2006.01) C07K 5/04 (2006.01) C07K 5/06 (2006.01)

Patent

CA 2539823

The present invention provides compounds having formula (I): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R1-R7, X1, X2, R, Q, and n are as defined herein.

La présente invention concerne des composés de formule (I) ainsi que des procédés de synthèse et des procédés d'utilisation de ces composés dans le traitement du cancer. Dans cette formule, R¿1?-R¿7?, X¿1?, X¿2?, R, Q et n sont tels que définis dans la description.

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