Hemiasterlin derivatives and uses thereof

Details Hemiasterlin derivatives and uses thereof Hemiasterlin derivatives and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 5/027 (2006.01) A61K 38/05 (2006.01) A61P 35/00 (2006.01) C07K 5/033 (2006.01) C07K 5/078 (2006.01) C07K 5/097 (2006.01)

Patent

CA 2479764

The present invention provides compounds having formula (I): (I) and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R1-R7, X1, X2, R, Q, and n are as defined herein.

L'invention concerne des composés représentés par la formule (I), dans laquelle R¿1?-R¿7?, X¿1?, X¿2?, R, Q et n sont tels que définis dans le descriptif. L'invention concerne également des méthodes de synthèse de ces composés et des méthodes d'utilisation de ces composés dans le traitement du cancer.

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