Hemodialysis monitoring system for hemodialysis machines

A - Human Necessities – 61 – M

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A61M 1/16 (2006.01) G06F 15/42 (1990.01)

Patent

CA 2124809

An improved on-line real time hemodialysis monitoring system for hemodialysis treatment. The hemodialysis monitoring system quantitates the rate arid amount of a constituent, such as urea, removedduring the hemodialysis treatment by measuring the constituent concentrations as a fonction of time in the spent dialysate effluent from a hemodialysis machine. A quantity of the spent dialysate effluent is removed from the dialysate effluent waste line periodically for testing. A urea concentration time profile can be analyzed to determine the urea removal, KT/V, URR, SRI and normalized protein catabolic rate (nPCR) indices. The hemodialysis monitoring system preferably can obtain a dialysate sample equilibrated with the blood prior to the start of a hemodialysis treatment. The hemodialysis monitoring system includes a two pool analysis for taking into account the constituent concentration differences in the extracellular and intracellular spaces in the hemodialysis patient during the hemodialysis treatment.

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