C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/18 (2006.01) A61K 38/18 (2006.01) C07K 14/475 (2006.01) C12N 1/21 (2006.01) C12N 5/02 (2006.01) C12N 5/10 (2006.01)
Patent
CA 2092542
Abstract A hemopoietic stem cell augmenting agent in which at least one type of hepatocyte growth factor is contained as an active component is provided. The hepatocyte growth factor has an augmenting activity on undifferentiated pluripotent hemopoietic stem cells and is useful as a hemopoietic stem cell augmenting agent for treatment of bone marrow suppression and for treatment of bone marrow malfunctions and furthermore is useful for in vitro growth of peripheral blood stem cells and bone marrow stem cells. Furthermore, a hepatocyte growth factor derived from human normal fibroblasts which is considered to be a type of hepatocyte growth factor can be obtained by genetic recombination techniques, and said factor is also useful as a hemopoietic stem cells augmenting agent.
Kawano Genji
Kojima Katsuaki
Komiyama Atsushi
Kubo Tetsuo
Nakahata Tatsutoshi
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Toray Industries Inc.
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