Hemostatic compositions containing sterile thrombin

A - Human Necessities – 61 – K

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A61K 38/48 (2006.01) C12N 9/74 (2006.01) C12Q 1/56 (2006.01)

Patent

CA 2534895

The present invention includes sterilized hemostatic compositions that contain a continuous, biocompatible liquid phase having a solid phase of particles of a biocompatible polymer suitable for use in hemostasis and that is substantially insoluble in the liquid phase, and sterile thrombin, each of which is substantially homogenously dispersed throughout the continuous liquid phase, and methods for making such compositions.

L'invention concerne des compositions hémostatiques stérilisés contenant une phase liquide biocompatible, continue, à phase solide de particules d'un polymère biocompatible convenant à une utilisation en hémostase et sensiblement insoluble en phase liquide, et de la thrombine stérile, ces deux composés étant dispersés de façon sensiblement homogène dans la phase liquide continue. L'invention concerne également des procédés de préparation de ces compositions.

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