Heparin-binding growth factor (hbgf) polypeptides

Details Heparin-binding growth factor (hbgf) polypeptides Heparin-binding growth factor (hbgf) polypeptides

A - Human Necessities

61

K

A61K 38/18 (2006.01) C07H 21/04 (2006.01) C07K 14/475 (2006.01) C07K 16/22 (2006.01) C07K 16/24 (2006.01) C12N 15/63 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2299411

Substantially pure heparin-binding growth factor polypeptides (HBGFs), nucleic acids encoding the HBGFs and antibodies which bind to the HBGFs of the invention are provided. The HBGF polypeptides are useful in methods for the induction of bone, cartilage and tissue formation, growth and development of the endometrium and in the acceleration of wound healing.

L'invention concerne des polypeptides du facteur de croissance se fixant à héparine (HBGF) sensiblement pure, des acides nucléiques codant ces HBGF et des anticorps se fixant à ces HBGF. Ces polypeptides de HBGF sont utiles dans des procédés servant à déclencher le croissance des tissus, des cartilages et des os et le développement de l'endomètre, ainsi qu'à accélérer la guérison de blessures.

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