Heparin for the treatment of ocular pathologies

Details Heparin for the treatment of ocular pathologies Heparin for the treatment of ocular pathologies

A - Human Necessities

61

K

A61K 31/727 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2557216

Formulations and methods useful to treat ocular neovascularization (new blood vessel growth in the cornea, retina, conjunctiva, and/or choroid) are disclosed. According to the invention there is provided a formulation suitable for the treatment of ocular neovascularization comprising heparin in a concentration and dose suitable for treating ocular neovascularization, characterized in that said compound is at a substantially neutral pH in a pharmaceutically acceptable form suitable for delivery to the eye. Use of drugs like steroids in the treatment of such ocular neovascularization ailments can increase intraocular pressure (glaucoma).

L'invention concerne des préparations et des méthodes utiles dans le traitement de la néovascularisation oculaire (croissance de nouveaux vaisseaux sanguins dans la cornée, la rétine, la conjonctive et/ou la choroïde). L'invention concerne plus particulièrement une préparation adaptée au traitement de la néovascularisation oculaire, contenant de l'héparine dans une concentration et à une dose adaptées audit traitement. Cette préparation se caractérise en ce que ledit composé présente un pH sensiblement neutre, sous une forme pharmaceutiquement acceptable, adaptée à une administration oculaire. L'utilisation de médicaments de type stéroïdes dans le traitement des maladies liées à la néovascularisation oculaire peut accroître la pression intra-oculaire (glaucome).

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