Heparin neutralization with platelet factor 4

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) A61K 38/19 (2006.01) A61K 31/725 (1990.01)

Patent

CA 2075957

2075957 9112017 PCTABS00006 Circulating heparin in a mammal may be neutralized without substantial depletion of platelets or leukocytes by administering to the mammal a heparin neutralizing amount of purified PF4 or rPF4 or a heparin neutralizing fragment thereof.

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