Heparin preparation

C - Chemistry – Metallurgy – 08 – B

Patent

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C08B 37/10 (2006.01)

Patent

CA 1108989

IMPROVED HEPARIN PREPARATION Abstract of the Disclosure A heparin preparation which exhibits elevated anti- coagulant activity and a process for producing the preparation. Conventional heparin exhibiting characteristic anticoagulant activity and molecular heterogeneity is incubated with anti- thrombin-heparin cofactor extracted from plasma. A portion of the heparin forms a complex with the cofactor. The uncomplexed heparin fraction is then separated from the complexed fraction, and the complexed fraction is broken down to produce cofactor and an active form of heparin.

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