Heparin-selective polymeric membrane electrode

Details Heparin-selective polymeric membrane electrode Heparin-selective polymeric membrane electrode

G - Physics

01

N

G01N 27/40 (2006.01) G01N 27/333 (2006.01)

Patent

CA 2117692

An anion exchange membrane (15) for ionic macromolecules, specifically heparin, which is formed of a polymeric matrix material, an anion exchange material suitable for heparin detection, and a plasticizer can be employed in an electrochemical sensor arrangement to directly measure the concentration of heparin ions in blood or blood fluid. Potentiometric response to heparin has been observed with membranes comprising 30-70 wt.% polymeric matrix material, such as polyvinyl chloride, 0.1-12 wt.% quaternary ammonium salt, such as tridodecyl methyl ammonium chloride, and 30- 70 wt.% of a plasticizer, such as dioctyl sebacate.

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