Heparinization of plasma treated substrates

A - Human Necessities – 61 – L

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204/96.17

A61L 27/00 (2006.01) A61L 33/00 (2006.01)

Patent

CA 1215676

Heparinization of Plasma Treated Substrates ABSTRACT OF THE DISCLOSURE The disclosure is of a method to improve the antithrombogenicity which results when heparin is attached to a polymeric surface The polymeric surface is activated by treatment with a plasma. The surface thus activated is rendered receptive to the binding of a surface active agent. The surface active agent in turn reacts with heparin to provide a polymeric surface of exceptional antithrombogeni- city when contacted with blood for an extended period of time.

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