Heparinized medical devices containing heparin-binding...

Details Heparinized medical devices containing heparin-binding... Heparinized medical devices containing heparin-binding...

A - Human Necessities

61

L

A61L 33/00 (2006.01) A61L 27/00 (2006.01) A61L 27/34 (2006.01) A61L 27/54 (2006.01) A61L 29/00 (2006.01) A61L 29/08 (2006.01) A61L 29/16 (2006.01) A61L 31/00 (2006.01) A61L 31/10 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2258154

Medical devices are coated with heparin and a heparin-binding growth factor- cytotoxic agent conjugate is bound to the heparin. The devices, including stents, are used to inhibit undesired cell proliferation or kill unwanted cells. A stent coated with heparin and bound with conjugate may be used to inhibit restenosis.

L'invention porte sur des instruments médicaux revêtus d'héparine ainsi que sur un conjugué d'agent cytotoxique et de facteur de croissance des fibroblastes (FGF) lié à l'héparine. Lesdits instruments, notamment les tuteurs, sont utilisés pour inhiber une prolifération indésirable de cellules ou pour éliminer des cellules indésirables. Un tuteur revêtu d'héparine et lié à un conjugué peut être utilisé pour inhiber la resténose.

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