C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/02 (2006.01) C12N 5/06 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2154701
A method for screening a chemical compound for hepatotoxicity or choleostatic potential, hepatic extraction potential, hepatic discharge into the bile, metabolic production or the ability to alter hepatic cell metabolism, using a primary hepatic cell culture with a functional bile canalicular network, is disclosed.
Hochman Jerome
Lecluyse Edward
Goudreau Gage Dubuc
Merck & Co. Inc.
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