Hepatic model

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/02 (2006.01) C12N 5/06 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2154701

A method for screening a chemical compound for hepatotoxicity or choleostatic potential, hepatic extraction potential, hepatic discharge into the bile, metabolic production or the ability to alter hepatic cell metabolism, using a primary hepatic cell culture with a functional bile canalicular network, is disclosed.

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