Hepatisis c virus nonstructural protein 4a (ns4a) is an...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/67 (2006.01) A61K 39/29 (2006.01) A61P 31/14 (2006.01) C07K 14/18 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2506525

The present invention concerns the discovery of an enhancer that regulates the expression of an associated gene. More particularly, it was found that the nonstructural protein 4A (NS4A) from the hepatisis C virus (HCV) modulates the expression and immunogenicity of an associated nucleic acid.

La présente invention a trait à la découverte d'un activateur qui assure la régulation de l'expression d'un gène associé. Plus particulièrement, on a découvert que la protéine 4A non structurelle (NS4A) dérivé du virus de l'hépatite C (VHC) module l'expression et l'immunogénécité d'un acide nucléique associé.

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