Hepatitis a virus vaccines

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/51 (2006.01) A61K 39/29 (2006.01) C07K 14/10 (2006.01) C12N 7/00 (2006.01)

Patent

CA 2144317

A live hepatitis A virus adapted to growth in MRC-5 cells, which HAV is preferably characterized by suitable attenuation for effective vaccine administration to humans and animals without inactivation, methods for adapting HAV to growth in MRC-5, vaccine compositions and method of vaccinating humans against HAV infection.

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