Hepatitis - a viruses adapted to human fibroblast cells

Details Hepatitis - a viruses adapted to human fibroblast cells Hepatitis - a viruses adapted to human fibroblast cells

A - Human Necessities

61

K

167/130, 195/33,

A61K 39/29 (2006.01) C12N 7/08 (2006.01) G01N 33/576 (2006.01)

Patent

CA 1196590

Abstract of the Disclosure Hepatitis-A virus, suitable for use in human or animal vaccines, is prepared by adapting the virus first to human kidney cells and subsequently adapting the thus-altered virus to human fibroblast strains. In the process the growth rate of Hepatitis-A virus on the noted tissues is materially increased. This HAV is also a useful antigen in diagnostic test procedures.

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