Hepatitis b monoclonal antibodies

Details Hepatitis b monoclonal antibodies Hepatitis b monoclonal antibodies

C - Chemistry, Metallurgy

12

N

C12N 15/51 (2006.01) A61K 31/70 (2006.01) A61K 39/29 (2006.01) A61K 39/42 (2006.01) A61K 48/00 (2006.01) C07K 14/02 (2006.01) C07K 16/08 (2006.01) C07K 16/42 (2006.01) C07K 16/46 (2006.01) C12N 5/18 (2006.01) G01N 33/576 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2252466

A monoclonal antibody that is capable of binding specifically to wild type HBsAg and to at least two mutant forms of HBsAg may be used in an improved immunoassay for the detection of both escape mutants and wild type HBsAg and may be used for passive immunisation against HBV.

Un anticorps monoclonal, capable de fixer spécifiquement l'antigène HBs de type sauvage et au moins deux formes mutantes dudit antigène, peut être utilisé dans un dosage immunologique amélioré pour la détection des deux antigènes HBs mutants à échappement ou de l'antigène sauvage, ainsi que pour l'immunisation passive contre le HBV.

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