Hepatitis b surface antigen formed by recombinant dna...

C - Chemistry – Metallurgy – 12 – N

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167/134, 167/37,

C12N 15/00 (2006.01) A61K 39/29 (2006.01)

Patent

CA 1340934

Bacterial plasmids carrying the PreS1-PreS2-S protein coding region, but lacking sequences encoding the hepatitis B core antigen, are used for transfection of eukaryotic cell lines for production of particles containing polypeptides encoded by the PreS1-PreS2-S protein coding region.

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