Hepatitis b vaccine

A - Human Necessities – 61 – K

Patent

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A61K 39/12 (2006.01) C07K 14/02 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1066191

ABSTRACT OF THE DISCLOSURE Hepatitis B antigen useful as vaccine is prepared from clarified plasma of hepatitis B donors by treating with pepsin at a pH wherein pepsin is enzyma- tically active, treating with urea, and optionally treating with formaldehyde.

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