Hepatitis b vaccine

Details Hepatitis b vaccine Hepatitis b vaccine

A - Human Necessities

61

K

167/130

A61K 39/29 (2006.01) C07K 14/02 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1237076

- 1 - Abstract: The invention provides a lyophilized prepara- tion of hepatitis B vaccine. The preparation comprises a stabilizer and an inactivated, purified hepatitis B virus surface antigen adsorbed on aluminum gel. The preparation is prepared by adding an aluminum gel and a stabilizer to an inactivated, purified hepatitis B virus surface antigen and lyophilizing the mixture, The lyophilized preparation can be kept stably for a long period of time without loos- ing its antigen titer and is useful for the prophylaxis of infection by hepatitis B virus.

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