Hepatitis c inhibitor peptides

Details Hepatitis c inhibitor peptides Hepatitis c inhibitor peptides

C - Chemistry, Metallurgy

07

K

C07K 14/81 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) A61K 38/55 (2006.01) A61P 31/14 (2006.01) C07K 1/10 (2006.01) C07K 5/10 (2006.01) C07K 5/107 (2006.01) C07K 7/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2336597

Formula (I) wherein a is 0 or 1; b is 0 or 1; Y is H or Cy, alkyl; B is H, an acyl derivative or a sulfonyl derivative; W is hydroxy or a N-substituted amino; or a pharmaceutically acceptable salt or ester thereof, for use in the treatment of hepatitis C virus (HCV) infection.

Peptides inhibiteurs de l'hépatite C ayant la formule (F) dans laquelle a est 0 ou 1; b est 0 ou 1; Y représente H ou alkyle C1-C6; B représente H, un dérivé acyle ou un dérivé sulfonyle; W représente hydroxy ou un amino N-substitué; ou un de leurs sels ou esters acceptables sur le plan pharmaceutique; ces peptides sont utiles dans le traitement d'une infection par le virus de l'hépatite C.

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