Hepatitis c virus cell culture system

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 7/02 (2006.01) C07K 14/02 (2006.01) C12N 5/10 (2006.01) C12N 7/00 (2006.01) C12N 15/51 (2006.01) C12N 15/86 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2303526

The hepatitis C virus (HCV) cell culture system according to the invention consists of human hepatoma cells, which are transfected with a HCV-RNA construct, that comprises the HCV specific RNA segments 5' NTR, NS3, NS4A, NS4B, NS5A, NS5B, and 3' NTR as well as a minimum of one marker gene for selection (selection gene).

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